Bria Defends her Master’s Thesis
April 22, 2024
Bria defended her thesis: "CD28 signaling upregulates phosphoenolpyruvate carboxykinase-2 (PCK2) to maintain T cell metabolic fitness.”
Best of luck in clinical trials at Arkansas Children’s Research Hospital!
Brian and Fen Receive $100,000 Award
April 3, 2024
Brian Koss, Ph.D. & Fen Xia, M.D., Ph.D. received $100,000 for the Winthrop P. Rockefeller Cancer Institute 2024 Team Science Award for "Exploring host GSK3β-53BP1 axis in immune control of tumor progression.”
Bria Wins the Eddie Reed Award
March 2024
Congratulations to Bria who won the Eddie Reed Award for Excellence in Cancer Research for her poster entitled, “Defining the role for PCK2 in T cell metabolic plasticity in glioblastoma”.
Sydnye Wins Two Awards
March 2024
Congratulations to Sydnye who won first place in the Professional Student category and runner up in the Cancer Research category for her poster entitled, “Proteome turnover dynamics profiling reveals destabilization of key metabolic machinery during T cell exhaustion”.
UAMS Student Research Day
March 2024
The Koss lab was represented well at this year’s Student Research Day, with trainees Sydnye, Jake, and Bria presenting posters. We look forward to seeing great contributions to cancer immunotherapy from these promising students.
Fall Mentor Award
December 2023
The Fall Mentor Award was presented to Dr. Brian Koss from Jessica Kelliher.
Congratulations Brian.
Congratulations, Jessica!
December 2023
Jessica defended her thesis “Molecular Mechanisms of the Phospho-Ubiquitin Axis in the Response to Double-Stranded Breaks.”
The Koss lab welcomes Jessica Lynn Kelliher, PhD as a postdoctoral fellow to the lab in January 2024.
Annual Biomedical Research Conference for Minoritized Scientists (ABRCMS)
November 2023
Bria Hampton, PhD Student
At this conference, Bria worked as a graduate student recruiter for UAMS alongside Dean Taverna. There were thousands of undergraduates interested in pursuing research and Bria informed them of the awesome graduate programs and PIs that UAMS has to offer.
SITC 2023
November 2023
38th Annual Meeting of the Society for Immunotherapy of Cancer (SITC 2023) San Diego, CA
- “EZH2 senses metabolic stress to restore MHC-I antigen presentation and ICB response in metastatic melanoma”, Jacob Edmondson
- “Defining the role for PCK2 in T-cell metabolic plasticity in Glioblastoma”, Bria Hampton
- “Induction of an intrinsic DNA damage response during T cell exhaustion”, Jessica Kelliher
- “Discovering T cell proteome turnover dynamics to enhance persistence in solid tumors”, Sydnye Shuttleworth
- “Functional and multi-omic characterization of CAR T cells across healthy donors”, Daniel Fil and Lora Rogers