News - The Koss Lab

katie cruse joins January 2025

Katie is enrolled UAMS in the GPIBS PhD program and will study the environmental impacts on T cell function and immunotherapy response.

thomas joins January 2025

Thomas is enrolled UAMS in the GPIBS PhD program and will study the role of PCK2 in T cell function during infiltration of solid tumors.

January 2025

Congratulations to Dr. Jessica Kelliher on receiving a highly competitive fellowship award from the American Cancer Society (ACS). Dr. Kelliher will use the $217,500, three-year award for a research project aimed at exploiting DNA repair in cell therapy for solid tumors.

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sitc 2024 November 2024

39th Annual Meeting of the Society for Immunotherapy of Cancer (SITC 2024) Houston, TX

“ATF6 activation in melanoma promotes anti-tumor immunity and improves ICB therapy response”, Jacob Edmondson
“Defining the role of PCK2 in T-cell metabolic plasticity in the solid tumor microenvironment”, Katie Wallis
“Inhibition of GSK3B-mediated 53BP1 T334 phosphorylation in T cells Enhances Infiltration and Cytotoxicity Against Head and Neck Squamous Cell Carcinoma”, Jessica Kelliher
“Comprehensive analysis of proteome turnover dynamics during T cell exhaustion”, Sydnye Shuttleworth
“Protecting EZH2 activity in T cells to increase melanoma therapy efficacy”, Megan Reed
“DNA Damage Repair Protein Modulation During T cell Exhaustion”, Kashti Shah

r21 award Congratulations to Tackett and Koss labs on receiving a $421,000 NCI R21 grant to study cancer-evolved resistance mechanism to enhance adoptive T-cells.

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anna SURF Anna participated in the eight-week Summer Undergraduate Research Fellowship (SURF) program, funded by the Department of Biochemistry and Molecular Biology. She focused on identifying E3 Ligases linked to T cell exhaustion. At the Arkansas Undergraduate Summer Research Symposium, she earned an award for having one of the top 10 posters out of 120! We enjoyed having Anna in the lab this summer!